ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations [Neuroscience]

ATM (ataxia-telangiectasia mutated) and ATR (ATM and Rad3-related) are large PI3 kinases whose human mutations result in complex syndromes that include a compromised DNA damage response (DDR) and prominent nervous system phenotypes. Both proteins are nuclear-localized in keeping with their DDR functions, yet both are also found in cytoplasm, including...

http://ift.tt/2qQzTm3