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Τρίτη 9 Ιανουαρίου 2018

Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1 [Biochemistry]

The voltage-dependent anion channel (VDAC) is the most abundant protein in the outer mitochondrial membrane and constitutes the primary pathway for the exchange of ions and metabolites between the cytosol and the mitochondria. There is accumulating evidence supporting VDAC's role in mitochondrial metabolic regulation and apoptosis, where VDAC oligomerization has...

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