What can we learn about predictors of atopy from birth cohorts and cord blood biomarkers?

Atopic disorders such as allergy and asthma are affecting children at an increasing rate.1 The reason for this increase and the precise mechanisms behind the development of allergic disorders in children are unclear. Factors such as family history, prenatal exposures, and early childhood exposures are each known to be involved in atopy development in children. The use of large-scale birth cohorts has presented a useful opportunity to study the relations among risk factors, potential biomarkers in cord blood, early life exposures, and their associations with atopy.

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