Have reducing tonsillectomy rates in England led to increasing incidence of invasive Group A Streptococcus infections in children?

Abstract

Objectives

To determine if there is a correlation between falling tonsillectomy numbers and increasing numbers of tonsillitis admissions and invasive Group A β-haemolytic streptococcus (iGAS) infection in children aged 14 and under in England.

Design

An observational cross-sectional study was performed.

Setting

The data extracted covered the period from 1991 until 2014.

Participants

Hospital admissions for tonsillectomies, tonsillitis/pharyngitis, and and all diagnoses of iGAS in children aged 14 and under who had a tonsillectomy.

Main outcome measures

Correlation between trends in tonsillectomies, tonsillitis/pharyngitis and iGAS.

Results

Across all age groups there was a dramatic reduction in the total number of tonsillectomies performed in England from 28,309 in 1990/1991, down to 6327 in 2013/2014 (77.7% reduction). The numbers of hospital admissions for management of acute tonsillitis and pharyngitis has risen dramatically. iGAS numbers have increased steadily over this time period and more than doubled in children aged 14 and under. There are significant negative correlations between the trend in iGAS infections and numbers of tonsillectomies in all ages. There are also strong positive correlations between the trend in numbers of tonsillitis episodes and the number of iGAS infections in all under14 year groups; the strongest correlation was seen in the 1-4 years age group (+0.92 Pearson correlation coefficient).

Conclusions

There appears to be a correlation between falling tonsillectomy numbers, increasing hospital admissions with tonsillitis and rising iGAS infection in England. Further studies are required to assess the aetiological role of tonsillitis in predisposing to iGAS infection and the potential societal benefit of tonsillectomies.

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