Staphylococcus aureus enhances the tight junction barrier integrity in healthy nasal tissue, but not in nasal polyps

Publication date: Available online 5 March 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Can Altunbulakli, Rita Costa, Feng Lan, Nan Zhang, Mubeccel Akdis, Claus Bachert, Cezmi A. Akdis

Teaser

Staphylococcus aureus infection increases the expression of the tight junctions (TJs) in healthy nasal tissue; while nasal polyps show decreased TJ expression at baseline and are unable to upregulate TJs to strengthen the epithelial barrier.


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