This study reported the prevalence of qnrVC genes in 74 ciprofloxacin-resistant Vibrio spp. isolates. Two novel functional qnrVC alleles, qnrVC8 and qnrVC9, sharing 98% and 99% nucleotide similarity with qnrVC6 and qnrVC7 respectively, were identified. Our findings suggested that carriage of qnrVC alleles, together with target mutations in gyrA and parC genes, may contribute to development of fluoroquinolone resistance in Vibrio species, posing serious threat to public health.
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