Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine

Hartley, JA; Flynn, MJ; Bingham, JP; Corbett, S; Reinert, H; Tiberghien, A; Masterson, LA; ... Howard, PW; + view all Hartley, JA; Flynn, MJ; Bingham, JP; Corbett, S; Reinert, H; Tiberghien, A; Masterson, LA; Antonow, D; Adams, L; Chowdhury, S; Williams, DG; Mao, S; Harper, J; Havenith, CEG; Zammarchi, F; Chivers, S; van Berkel, PH; Howard, PW; - view fewer (2018) Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine. Scientific Reports , 8 , Article 10479. 10.1038/s41598-018-28533-4 . Green open access

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