Reply to Huang et al.: Avoiding “one-size-fits-all” approaches to variant discovery [Biological Sciences]

Huang et al. (1) argue that variant calling methods less conservative than GATK's Best Practices workflow (2) increased false-positive variant discovery in our study of wild and cultivated potatoes (3), impacting diversity estimates. We disagree with their conclusion and highlight the rationale for the variant calling methods used in our...

https://ift.tt/2un0GVv