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Τρίτη 3 Ιουλίου 2018

Timing of DNA damage responses impacts persistence to fluoroquinolones [Microbiology]

Bacterial persisters are subpopulations of phenotypic variants in isogenic cultures that can survive lethal doses of antibiotics. Their tolerances are often attributed to reduced activities of antibiotic targets, which limit corruption and damage in persisters compared with bacteria that die from treatment. However, that model does not hold for nongrowing...

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