Genetic correlation of antibiotic susceptibility and resistance genotyping for Mycobacterium abscessus group [Mechanisms of Resistance]

Treatment efficacy of Mycobacterium abscessus infections depends on bacterial genotype. Here the relationship between genotype, as determined using sequence analysis, and antibiotic resistance phenotype was analyzed. The results demonstrate that Mycobacterium abscessus genotype characteristics, including erm(41) sequevar, and mutations of rrl and rrs, are predictive of clarithromycin and amikacin resistance.

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