Background Many chemicals used for fragrance purposes in a diversity of products have allergenic potential. Based on such concerns, industry groups developed concentration limits for use of fragrance chemicals in personal care and cosmetic products. Objective The aim of this study was to use a quantitative risk assessment to evaluate the potential for skin sensitization induction resulting from daily exposure to fragrance chemicals present in personal care and cosmetic products. Methods Product-specific dermal consumer exposure levels were calculated based on product use data in US adult females and benchmarked against acceptable exposure levels based on reported no expected sensitization induction levels to determine a margin of safety for each fragrance under evaluation. Conclusions The results demonstrate an increased risk of skin sensitization induction for several leave-on products (lipstick, solid antiperspirant, eye shadow, face cream) for most of the evaluated fragrance chemicals, particularly under high-use exposure scenarios. In contrast, rinse-off products (shampoo, conditioner, facial cleanser) were not associated with risk of skin sensitization induction. Because the approach was based on maximum use limits for fragrance chemicals with skin sensitization concerns, the results suggest these limits may not be protective, particularly in the United States.
https://ift.tt/2z97qcE
Αρχειοθήκη ιστολογίου
-
►
2020
(289)
- ► Φεβρουαρίου (28)
-
►
2019
(9071)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3642)
- ► Ιανουαρίου (3200)
-
▼
2018
(39872)
- ► Δεκεμβρίου (3318)
-
▼
Νοεμβρίου
(3567)
-
▼
Νοε 16
(118)
- Effects of hypothermia during propofol anesthesia ...
- Roles of inflammation, neurogenic inflammation, an...
- Bridging the gap between vaccination with Bacille ...
- Progressive annular verrucous erosive plaques on t...
- Voice therapy associated with a decrease in the re...
- Cutaneous squamous cell carcinoma metastasis to th...
- Sex bias: Is it pervasive in otolaryngology clinic...
- Tracheostomy demographics and outcomes among pedia...
- Long‐term swallowing performance following transor...
- Impact of a Formal Patient Safety and Quality Impr...
- Evolving phenotype of the head and neck surgeon
- Real‐time robotic airway measurement: An additiona...
- Dysfunctional hypoglossal nerve stimulator after e...
- Are chronic cough and laryngopharyngeal reflux mor...
- Give Thyroid Health on #GivingTuesday, November 27
- Postoperative myxedema coma in patients undergoing...
- MiR-196b affects the progression and prognosis of ...
- What is melasma?
- Shaved hair style scalp medical tattooing techniqu...
- Secretory carcinoma: the eastern Canadian experien...
- Skin Diseases of the Breast and Nipple Part 2: Inf...
- Skin Diseases of the Breast and Nipple Part I: Ben...
- A simple technique to increase field of view (FOV)...
- SELF-ASSESSMENT
- North American Contact Dermatitis Group Patch Test...
- Orthodontic Appliance Intolerance Due to Dental Ad...
- Trends in Patch Testing With the Mayo Clinic Stand...
- Dupilumab as a Treatment for Allergic Contact Derm...
- Associations of Nickel Co-Reactions and Metal Poly...
- Patch Testing by Anton C. de Groot
- Comparison of Nickel Sulfate 2.5% and Nickel Sulfa...
- Cannabidiol-Induced Acute Generalized Exanthematou...
- Skin Sensitization Induction Potential From Daily ...
- Erythema Multiforme Major After Immunotherapy With...
- Isothiazolinone in Residential Interior Wall Paint...
- Contact Allergy to Propylene Glycol and Cross-Reac...
- Moisturizers: A Comparison Based on Allergens and ...
- Long-term Likelihood of Patch Testing, Academic Pr...
- Eating Healthy During the Holidays
- Complements from the Lung
- Follow‐up of patients with negative drug provocati...
- Th2 cell differentiation from naive CD4+ T cells i...
- The Quality of Reporting Randomised Controlled Tri...
- Antihelix/helix violaceous macules in Japanese pat...
- Heterogeneity of PD‐L1 Expression in a Case of Mer...
- Cross‐sectional associations between cutaneous vir...
- The views of consultant dermatologists on creating...
- Unilesional mycosis fungoides is associated with i...
- Journées dermatologiques de Paris 2018
- Secretory carcinoma: the eastern Canadian experien...
- Three versus five lumbar paravertebral injections ...
- The temperature dependence of C-H⋯F-C interactions...
- Spinal cord involvement in multiple sclerosis and ...
- Code similarity and clone search in large-scale so...
- Impact of social determinants on antiretroviral th...
- The impact of simulated interviews for individuals...
- Cytokine responses to exercise and activity in pat...
- Investigating the quality of the diet of foodbank ...
- Transducer-based evaluation of tremor
- A type III complement factor D deficiency: Structu...
- Predicting global killer whale population collapse...
- Investigating the Combustion and Emissions Charact...
- The Awesome and Capricious Language of Past, Prese...
- Remote Sensing of Kelp (Laminariales, Ochrophyta):...
- Operationalising the use of Life Cycle Assessment ...
- SLC39A14 mutations expand the spectrum of manganes...
- Face identity matching is selectively impaired in ...
- Clinical and laboratory features of seventy-eight ...
- Mouse models of kufor-rakeb disease link Parkinson...
- Korea container ports and spatial effects on manuf...
- Fear processing is differentially affected by late...
- Natural history of untreated squamous cell carcino...
- SCT200 Injection in Patients With Head and Neck Sq...
- EffectiveNess of Low-dose Aspirin in Prevention of...
- Anterior chamber fibrinoid syndrome after cataract...
- Ring chromosome 15 – cytogenetics and mapping arra...
- Estrogen receptor-alpha (ESR1) polymorphism rs1999...
- Cyberspace and International Order
- Degradation kinetics of organic matter in dairy in...
- Simplified lipid II-binding antimicrobial peptides...
- Dynamical decoupling based quantum sensing: Floque...
- Mining of Ebola virus entry inhibitors identifies ...
- Decline in sexuality and wellbeing in older adults...
- Isolation and characterisation of mouse intestinal...
- Assessing health risks associated with municipal s...
- Intratumoral immunotherapy with XCL1 and sFlt3L en...
- Characterizing the Short-Term Habituation of Event...
- How to incorporate patient and public perspectives...
- Hypertension prevalence, awareness, treatment and ...
- Implementing multiple health behaviour change inte...
- PRC2 is dispensable for HOTAIR-mediated transcript...
- Determinants of attitudes and beliefs toward human...
- Inactivation of Escherichia coli and Salmonella wi...
- Neocerebellar Crus I abnormalities associated with...
- Survey design for exploring demand for Mobility as...
- Employee control over scheduling of shifts and obj...
- Permanent night workers' sleep and psychosocial fa...
- IMPROVING THE QUALITY OF DATA PRESENTATION IN HEAL...
- SLAMF receptors on normal and malignant B cells
- Mechanisms and functions of IL-17 signaling in ren...
-
▼
Νοε 16
(118)
- ► Σεπτεμβρίου (3683)
- ► Φεβρουαρίου (2693)
- ► Ιανουαρίου (3198)
-
►
2017
(41099)
- ► Δεκεμβρίου (3127)
- ► Σεπτεμβρίου (2173)
-
►
2016
(13807)
- ► Δεκεμβρίου (700)
- ► Σεπτεμβρίου (600)
- ► Φεβρουαρίου (1350)
- ► Ιανουαρίου (1400)
-
►
2015
(1500)
- ► Δεκεμβρίου (1450)
Ετικέτες
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου