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Δευτέρα 14 Δεκεμβρίου 2015

Conversion of a non-heme iron-dependent sulfoxide synthase into a thiol dioxygenase by a single point mutation

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Chem. Commun., 2015, Accepted Manuscript
DOI: 10.1039/C5CC07772A, Communication
Kristina V Goncharenko, Florian Peter Seebeck
EgtB from Mycobacterium thermoresistibile catalyzes O2-dependent sulfur-carbon bond formation between the side chains of N[small alpha]-trimethyl histidine and [gamma]-glutamyl cysteine as a central step in ergothioneine biosynthesis. A single point mutation...
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