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Δευτέρα 14 Δεκεμβρίου 2015

Organocatalytic Enantio- and Diastereoselective Synthesis of 3,5-Disubstituted Prolines

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Chem. Commun., 2015, Accepted Manuscript
DOI: 10.1039/C5CC09329E, Communication
Iker Riano, Estibaliz Diaz, Uxue Uria, Efraim Reyes, Luisa Carrillo, Jose L Vicario
The asymmetric synthesis of substituted pyrrolidines has been accomplished using a novel organocatalytic cyclization reaction promoted by a Cinchona alkaloid base primary amine. The reaction proceeds smoothly yielding pyrrolidine-2,2-dicarboxylates after...
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