New Photochemical Approaches to the Bilobalide Core

Bilobalide is a tetracyclic sesquiterpene containing three contiguous γ-lactone rings and an unusual tert-butyl group which is found in the leaves of the ginkgo tree (Ginkgo biloba). Three different photochemical approaches towards bilobalide's unique skeleton are presented. A meta-photocycloaddition, a [2 + 2]-photocycloaddition, and a Paternò-Büchi-reaction were chosen as the respective key steps.

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