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Τρίτη 6 Ιουνίου 2017

Enantioselective synthesis of tetrahydrocyclopenta[b]indole bearing a chiral quaternary carbon center via Pd(II)-SPRIX-catalyzed C-H activation

Chem. Commun., 2017, Accepted Manuscript
DOI: 10.1039/C7CC03199H, Communication
Mohamed A Abozeid, Shiho Sairenji, Shinobu Takizawa, Makoto Fujita, Hiroaki Sasai
The highly enantioselective cyclization of 3-alkenylindole via C-H activation has been established using Pd(OCOCF3)2 in conjunction with the chiral spiro bis(isoxazoline) ligand (SPRIX). The presence of an N-allyl substituent on...
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