Spatiotemporal reorganization of the reading network in adult dyslexia

Publication date: Available online 24 April 2017
Source:Cortex
Author(s): Eddy Cavalli, Pascale Colé, Chotiga Pattamadilok, Jean-Michel Badier, Christelle Zielinski, Valérie Chanoine, Johannes C. Ziegler
Developmental dyslexia is characterized by impairments in reading fluency and spelling that persist into adulthood. Here, we hypothesized that high-achieving adult dyslexics (i.e., university students with a history of dyslexia) manage to cope with these deficits by relying to a greater extent on morphological information than do non-impaired adult readers. We used magnetoencephalography (MEG) in a primed lexical decision task, in which we contrasted orthographic, morphological and semantic processing. Behavioral results confirmed that adult dyslexics did indeed rely to a greater extent on the semantic properties of morphemes than controls. In line with this, MEG results showed early morphological effects (100-200ms) in a frontal network, which reflected the contribution of semantic processing. The same effects occurred much later in controls (∼400ms). In contrast, controls showed early orthographic priming effects in posterior left inferior temporal gyrus at around 130ms, which were not seen in dyslexics. In the left inferior temporal gyrus, dyslexics showed only late activation of semantic and orthographic information. The present results suggest a spatiotemporal reorganization of the reading network, in which morphological information located in frontal regions is activated earlier in high-achieving adults dyslexics than controls.



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