Functional genomics in Brugia malayi reveal diverse muscle nAChRs and differences between cholinergic anthelmintics [Pharmacology]

Many techniques for studying functional genomics of important target sites of anthelmintics have been restricted to Caenorhabditis elegans because they have failed when applied to animal parasites. To overcome these limitations, we have focused our research on the human nematode parasite Brugia malayi, which causes elephantiasis. Here, we combine single-cell...

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