Small molecule inhibits {alpha}-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons [Neuroscience]

Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons, a process that current therapeutic approaches cannot prevent. In PD, the typical pathological hallmark is the accumulation of intracellular protein inclusions, known as Lewy bodies and Lewy neurites, which are mainly composed of α-synuclein. Here, we exploited a...

https://ift.tt/2ypRTE9