Hailey–Hailey disease with classic pemphigus vulgaris pathology: A case study

The patient is a 61-year-old white female with a 2-year history of painful and pruritic rash that began on the neck and progressed to involve the face, eyelids, scalp, neck, chest, back, bilateral upper extremities, axillae, popliteal fossae, and the groin. The patient has multiple family members with the same condition. Examination of the skin revealed erythematous macerated eroded plaques involving over 60% BSA. No mucosal or nail changes were identified. The patient had failed multiple therapies including topical and oral steroids, acitretin, dapsone, and valacyclovir.

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