Pancreatic panniculitis sans pancreatitis in a newly diagnosed diabetes mellitus patient

Pancreatic panniculitis is a rare inflammatory disease affecting the subcutis in a small percentage of patients with pancreatic disease, postulated to be due to enzymatic degradation of adipose tissue by pancreatic lipase and amylase. Elevated serum lipase and amylase levels can occur in patients with diabetic ketoacidosis (DKA), even without evidence of pancreatitis. We report a case of a newly diagnosed diabetes mellitus patient presenting with DKA and subsequent pancreatic panniculitis lesions over her lower limbs, but without evidence of pancreatitis.

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