Publication date: Available online 26 August 2020Source: Clinical NeurophysiologyAuthor(s): Glenn H. M. Calvert, Roisin McMackin, Richard G. Carson
Wed Aug 26, 2020 14:27
Publication date: Available online 26 August 2020Source: Clinical NeurophysiologyAuthor(s): Maria O. Kovalchuk, Hessel Franssen, Leonard H. van den Berg, Leonard J. van Schelven, Boudewijn T.H.M. Sleutjes
Wed Aug 26, 2020 14:27
Publication date: Available online 26 August 2020Source: Clinical NeurophysiologyAuthor(s): Shreya Louis, Andrew Dhawan, Christopher Newey, Dileep Nair, Lara Jehi, Stephen Hantus, Vineet Punia
Wed Aug 26, 2020 14:27
Publication date: Available online 26 August 2020Source: Clinical NeurophysiologyAuthor(s): Harold A. Rocha, John Marks, Adam J. Woods, Roland Staud, Kimberly Sibille, Andreas Keil
Wed Aug 26, 2020 14:27
Publication date: Available online 25 August 2020Source: Clinical NeurophysiologyAuthor(s): Krit Charupanit, Indranil Sen-Gupta, Jack J Lin, Beth A Lopour
Wed Aug 26, 2020 14:27
Abstract Cinnamaldehyde (CA), as an active compound isolated from the bark of Cinnamomum cassia, has been reported to possess the anti-fungal, anti-bacterial, anti-inflammatory, anti-mutagenic, and anti-oxidant properties. However, the possible effects and underlying mechanisms of CA on rheumatoid arthritis (RA) have not been revealed yet. In the present study, we found that CA obviously improved the type II collagen-induced RA in rats,...
Wed Aug 26, 2020 03:00
Key points Muscle‐specific genetic ablation of PAK2, but not whole‐body PAK1 knockout, impairs glucose tolerance in mice Insulin‐stimulated glucose uptake partly relies on PAK2 in glycolytic EDL muscle Contrasting previous reports, PAK1 is dispensable for insulin‐stimulated glucose uptake in mouse muscle Abstract The group I p21‐activated kinase (PAK) isoforms PAK1 and PAK2 are activated in response to insulin in skeletal muscle and PAK1/2 signalling is impaired in insulin‐resistant...
Wed Aug 26, 2020 11:39
Key points The Arg271Gln mutation of the glycine receptor (GlyR) causes hereditary hyperekplexia. This mutation dramatically compromises GlyR function; however, the underlying mechanism is not yet known. This study, by employing function and computation methods, proposes that charged residues (including the Arg residue) at the pore extracellular half from each of the five subunits of the homomeric α1 GlyR, create an electrostatic repulsive potential to widen the pore, thereby facilitating channel...
Wed Aug 26, 2020 11:04
Key Points Summary LAT4 is a broadly expressed uniporter selective for essential branched chain amino acids, methionine and phenylalanine that is involved in epithelial transport. Its global deletion leads to an early malnutrition‐like phenotype and death within 10 days after birth. Here we tested the impact of deleting LAT4 selectively in mouse intestine. This affected slightly the absorption of amino acids (AAs) and delayed gastrointestinal motility, however had no major phenotypic effect,...
Tue Aug 25, 2020 20:02
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου