Related Articles Effectiveness of Levetiracetam Monotherapy in Pediatric Patients With Epilepsy. J Child Neurol. 2019 09;34(10):593-597 Authors: Mazur RD, Wang Ba Q, Kato Bs K, Buchsbaum Bs R, Bonito Bs J, Choi H, Hirsch L, Detyniecki K Abstract The main objective of this study was to assess the efficacy, safety, and retention rates of levetiracetam monotherapy in children with epilepsy. A retrospective review of pediatric patients receiving...
Wed Aug 26, 2020 13:34
Related Articles The Expanding Clinical Universe of Polyglutamine Disease. Neuroscientist. 2019 10;25(5):512-520 Authors: Huang S, Zhu S, Li XJ, Li S Abstract Polyglutamine (polyQ) diseases are a group of hereditary neurodegenerative disorders caused by expansion of unstable polyQ repeats in their associated disease proteins. To date, the pathogenesis of each disease remains poorly understood, and there are no effective treatments. Growing...
Wed Aug 26, 2020 13:34
Related Articles Multiple sclerosis in a young woman with sickle cell disease. Mult Scler Relat Disord. 2020 Jul 28;45:102427 Authors: Kerpen K, Baptiste A, Yeshokumar AK Abstract BACKGROUND: Comorbidities can impose diagnostic and treatment challenges in patients with multiple sclerosis (MS). Sickle cell disease (SCD) and MS are both inflammatory diseases featuring immune system dysregulation, and the reciprocal interaction of these diseases...
Wed Aug 26, 2020 14:57
Related Articles Ovarian cancer prognosis in women with endometriosis. A retrospective nationwide cohort study of 32,419 women. Am J Obstet Gynecol. 2020 Aug 22;: Authors: Hermens M, van Altena AM, van der Aa M, Bulten J, van Vliet HA, Siebers AG, Bekkers RL Abstract BACKGROUND: Contradicting results regarding ovarian cancer prognosis in women with endometriosis have been reported in the literature. Due to the small sample size of previous...
Wed Aug 26, 2020 14:57
Related Articles An update on the immune landscape in lung and head and neck cancers. CA Cancer J Clin. 2020 Aug 25;: Authors: Carlisle JW, Steuer CE, Owonikoko TK, Saba NF Abstract Immunotherapy has dramatically changed the treatment landscape for patients with cancer. Programmed death-ligand 1/programmed death-1 checkpoint inhibitors have been in the forefront of this clinical revolution. Currently, there are 6 US Food and Drug Administration-approved...
Wed Aug 26, 2020 13:57
Related Articles Guideline-based indicators for adult patients with myelodysplastic syndromes. Blood Adv. 2020 Aug 25;4(16):4029-4044 Authors: Stojkov K, Silzle T, Stussi G, Schwappach D, Bernhard J, Bowen D, Čermák J, Dinmohamed AG, Eeltink C, Eggmann S, Fenaux P, Germing U, Haschke M, Hellstrom-Lindberg E, Heger M, van de Loosdrecht AA, Passweg J, Pfeilstöcker M, Platzbecker U, Malcovati L, de Almeida AM, Mittelman M, Morgenthaler C, Steensma DP, Santini...
Wed Aug 26, 2020 13:57
Related Articles [Prospects and challenges of exosomes as drug delivery systems]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2020 Aug 25;37(4):714-720 Authors: Meng W, Li L, Zhu G Abstract Exosomes are nanoscale vectors with a diameter of 30~100 nm secreted by living cells, and they are important media for intercellular communication. Recent studies have demonstrated that exosomes can not only serve as biomarkers for diagnosis, but also have...
Wed Aug 26, 2020 13:57
Related Articles Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study. Inj Prev. 2020 Aug 24;: Authors: James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, Liu Z, Roberts NLS, Sylte DO, Bertolacci GJ, Cunningham M, Henry NJ, LeGrand KE, Abdelalim A, Abdollahpour I, Abdulkader RS, Abedi A, Abegaz KH, Abosetugn AE, Abushouk AI, Adebayo OM, Adsuar JC, Advani SM, Agudelo-Botero M, Ahmad T, Ahmed...
Wed Aug 26, 2020 13:57
Related Articles What is our threshold: Departmental planning for radiation oncology's future in the time of COVID-19. Radiother Oncol. 2020 08;149:46-47 Authors: Chandra RA, Thomas CR PMID: 32389753 [PubMed - indexed for MEDLINE]
Wed Aug 26, 2020 13:57
Related Articles Efficacy of PI3K inhibitors in advanced breast cancer. Ann Oncol. 2019 12;30 Suppl 10:x12-x20 Authors: Verret B, Cortes J, Bachelot T, Andre F, Arnedos M Abstract The phosphoinositide 3 (PI3)-kinase/Akt signaling pathway has always been a focus of interest in breast cancer due to its role in cell growth, cell proliferation, cell migration and deregulated apoptosis. Its activation has been linked to endocrine resistance and...
Wed Aug 26, 2020 13:57
Related Articles Evaluation of cardiomyopathy in acute myeloid leukemia patients treated with anthracyclines. J Oncol Pharm Pract. 2020 Apr;26(3):680-687 Authors: Mort MK, Sen JM, Morris AL, DeGregory KA, McLoughlin EM, Mort JF, Dunn SP, Abuannadi M, Keng MK Abstract BACKGROUND: Acute myeloid leukemia patients receive anthracycline-containing induction chemotherapy. Anthracyclines cause cardiotoxicity; however, there is a paucity of data reflecting...
Wed Aug 26, 2020 13:57
Related Articles Palliative care for people living with heart failure: European Association for Palliative Care Task Force expert position statement. Cardiovasc Res. 2020 01 01;116(1):12-27 Authors: Sobanski PZ, Alt-Epping B, Currow DC, Goodlin SJ, Grodzicki T, Hogg K, Janssen DJA, Johnson MJ, Krajnik M, Leget C, Martínez-Sellés M, Moroni M, Mueller PS, Ryder M, Simon ST, Stowe E, Larkin PJ Abstract Contrary to common perception, modern palliative...
Wed Aug 26, 2020 13:57
Related Articles The role of ado-trastuzumab emtansine in current clinical practice. J Oncol Pharm Pract. 2020 Aug 24;:1078155220951862 Authors: Turshudzhyan A Abstract OBJECTIVE: This review reflects the literature from 2019 to 2020 on ado-trastuzumab emtansine's (T-DM1) therapeutic use, clinical controversies, and newest perspectives on use.Data sources: PubMed was used as a database. Search "ado-trastuzumab emtansine" on June 11th, 2020 resulted...
Wed Aug 26, 2020 16:14
[A comparative study on treatment of severe OSA with UPPP combined with endoscopic low-temperature plasma tongue root resection]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr;34(4):324-328 Authors: Ji Y, Li Q, Zhang Y, Xin F, Liu R, Dong R, Zhao C Abstract Objective:The aim of this study is to investigate the effect of modified uvulopalatopharyngoplasty （UPPP） combined with endoscopic hypothermic Plasma glossectomy （Eco-TBR） on...
Wed Aug 26, 2020 14:40
[The value of improved Mallampati grading combined with NoSAS in OSA screening]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr;34(4):320-324 Authors: Liu K, Zhang Y Abstract Objective:To evaluate the value of improved Mallampati grading combined with NoSAS questionnaire in screening for obstructive sleep apnea （OSA）. Method:A total of 344 patients admitted to our hospital for sleep disorders were studied. All patients were measured...
Wed Aug 26, 2020 14:40
[The value of the pharyngeal airway pressure monitoring test in topodiagnosis of OSA]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr;34(4):296-300 Authors: Pang F, Deng W, Liu J, Yu E, Zhang X Abstract Objective:To analyses the value of an improved methods of Muller's test, pharyngeal airway pressure monitoring test（PAPMT）, in topodiagnosis of OSA. Method:One hundred and one cases with OSA（AHI≥5 times per hour） and 30 normal adults...
Wed Aug 26, 2020 14:40
[Correlation between peripheral blood Th17 cells and carotid intima-media thickness in OSA patients]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Aug;34(8):747-751 Authors: Zhang N, Li Y, Li B, Xu W Abstract Objective:To study the carotid intima-media thickness （IMT） level of OSA patients of different severity, the proportion of Th17 cells in peripheral blood and the mRNA level of nuclear transfer factor RORγt, and to explore the relationship...
Wed Aug 26, 2020 14:40
[Comparison and intervention of differences in upper airway obstruction in children with OSAS between awake and asleep]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Aug;34(8):713-718 Authors: He S, Zhang R, Ma S, Chen J Abstract Objective:Drug induced sleep endoscopy（DISE） is a useful tool to locate the upper airway obstructions in patients with obstructive sleep apnea syndrome（OSAS）. The goal of our research was to compare the sites,...
Wed Aug 26, 2020 14:40
[Analysis of genetic and environmental risk factors in pediatric OSA]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Aug;34(8):678-682 Authors: Wang H, Li Y, Gao F, Zhao G, Su M, Kang D, Xu W, Han D Abstract Objective:To investigate the genetic and family environmental risk factors of obstructive sleep apnea（OSA） in children with habitual snoring. Method:Children with habitual snoring who underwent overnight PSG were recruited. Subjects...
Wed Aug 26, 2020 14:40
[The efficacy of OM85-BV in the treatment of recurrent upper respiratory tract infection with adenoid hypertrophy and the preliminary exploration of potential therapeutic mechanism]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jun;34(6):499-504 Authors: Chen W, Cao W, Shen J, Zhou Z, Chen C, Fu Y Abstract Objective:To observe the efficacy of OM85-BV in the treatment of recurrent upper respiratory tract infection with adenoid hypertrophy...
Wed Aug 26, 2020 14:40
[The significance of evaluation of sleep respiration in infants with Pierre Robin sequence]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jun;34(6):496-498 Authors: Zhong J, Luo X, Huang Z, Qiu S, Cheng C, Yang L, Yi X, Zeng J, Liu D Abstract Objective:This study aimed to evaluate the sleep disorders of infants with Pierre Robin sequence by PSG, and to understand the sleep breathing characteristics of them. Method:Seventeen patients...
Wed Aug 26, 2020 14:40
Related Articles Lung to finger circulation time in sleep study and coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis. Sleep Med. 2020 Jun 03;75:8-11 Authors: Kwon Y, Mariani S, Reid M, Jacobs D, Lima J, Kapur V, Punjabi N, Redline S Abstract BACKGROUND: Lung to finger circulation time (LFCT) measured from sleep studies may represent a novel physiologic marker for cardiovascular risk in patients with sleep disordered breathing...
Wed Aug 26, 2020 14:40
Symptom subtypes and cognitive function in a clinic-based OSA cohort: a multi-centre Canadian study.
Related Articles Symptom subtypes and cognitive function in a clinic-based OSA cohort: a multi-centre Canadian study. Sleep Med. 2020 May 11;74:92-98 Authors: Allen AH, Beaudin AE, Fox N, Raneri JK, Skomro RP, Hanly PJ, Mazzotti DR, Keenan BT, Smith EE, Goodfellow SD, Ayas NT Abstract BACKGROUND: Distinct symptom subtypes are found in patients with OSA. The association between these subtypes and neurocognitive function is unclear. OBJECTIVE:...
Wed Aug 26, 2020 14:40
Related Articles Obstructive sleep apnea in Parkinson's disease. Sleep Med. 2020 May 21;74:91 Authors: Kawada T PMID: 32841851 [PubMed - as supplied by publisher]
Wed Aug 26, 2020 14:40
Related Articles Management of sleep apnea in New York City during the COVID-19 pandemic. Sleep Med. 2020 Jul 18;74:86-90 Authors: Thorpy M, Figuera-Losada M, Ahmed I, Monderer R, Petrisko M, Martin C, Akhtar J, Thorpy J, Haines C Abstract BACKGROUND: With the onset of the COVID-19 outbreak there has been concern that patients with obstructive sleep apnea (OSA) who develop COVID-19 may be at risk of greater morbidity and mortality than patients...
Wed Aug 26, 2020 14:40
Related Articles Prevalence of chronic kidney disease in obesity hypoventilation syndrome and obstructive sleep apnoea with severe obesity. Sleep Med. 2020 May 21;74:73-77 Authors: Sivam S, Yee BJ, Chadban SJ, Piper AJ, Hanly PJ, Wang D, Wong KKH, Grunstein RR Abstract PURPOSE: Chronic kidney disease (CKD) is common in severe obstructive sleep apnoea (OSA), however prevalence in obesity hypoventilation syndrome (OHS) is not known. This study...
Wed Aug 26, 2020 14:40
Related Articles Sleep-disordered breathing in cystic fibrosis. Sleep Med. 2020 Jun 05;74:57-65 Authors: Shakkottai A, Nasr SZ, Hassan F, Irani S, O'Brien LM, Chervin RD Abstract INTRODUCTION: Cystic fibrosis (CF) is a life-shortening, genetic disease that affects approximately 30,000 Americans. Although patients frequently report snoring, mouth breathing, and insomnia, the extent to which sleep-disordered breathing (SDB) may underlie these...
Wed Aug 26, 2020 14:40
Related Articles Patterns of nightly CPAP usage in OSA patients with suboptimal treatment adherence. Sleep Med. 2020 Jun 11;74:109-115 Authors: Grewe FA, Bradicich M, Gaisl T, Roeder M, Thiel S, Sievi NA, Kohler M Abstract BACKGROUND AND OBJECTIVES: Low adherence impairs the effectiveness of continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnoea (OSA), but knowledge on CPAP usage micro-patterns is mostly...
Wed Aug 26, 2020 14:40
Related Articles First interventional exchange of a left transvenous phrenic nerve stimulation lead from the novel remedē system - case report. J Cardiovasc Electrophysiol. 2020 Aug 25;: Authors: Gutleben KJ, Eitz T, Westlund R, Gummert JF, Sommer P, Fox H Abstract The remedē System is a novel fully implantable transvenous phrenic nerve stimulation (TPNS) device developed to treat central sleep apnea. No information is published how to explant...
Wed Aug 26, 2020 14:40
Related Articles [Sleep efficiency in level II polysomnography of hospitalized and outpatients]. Medicina (B Aires). 2020;80(4):317-323 Authors: Blanco M, Ernst G, Valiensi S, Berrozpe E, Martínez O, Borsini E Abstract Polysomnography without real-time technical supervision (sleep test level II) h as been described with adequate quality of neurological and respiratory signals. We compare the efficiency and quality of sleep in hospitalized patients...
Wed Aug 26, 2020 14:40
Related Articles What predicts the unsuccess of bariatric surgery? An observational retrospective study. J Endocrinol Invest. 2020 Aug 25;: Authors: D'Eusebio C, Boschetti S, Rahimi F, Fanni G, De Francesco A, Toppino M, Morino M, Ghigo E, Bo S Abstract PURPOSE: Bariatric surgery (BS) has been recognized as an effective treatment for most patients with morbid obesity, but a variable range of patients failed to achieve a successful weight-loss....
Wed Aug 26, 2020 14:40
Related Articles Comparison of commonly used screening tools for determining obstructive sleep apnea amongst aviation employees. Sleep Med. 2020 Jul 30;: Authors: Arora T, Al-Houqani M Abstract INTRODUCTION: Epidemiological evidence suggests the prevalence of Obstructive Sleep Apnea (OSA) ranges 9-38%. Multiple screening tools are used to aid diagnosis. In professions that require high levels of attentiveness, safety, and responsibility for...
Wed Aug 26, 2020 14:40
Related Articles Evaluation of bendopnea in severe obstructive sleep apnea syndrome. Med Clin (Barc). 2020 Aug 21;: Authors: Baeza-Trinidad R, Roncero-Lazaro A, Mosquera-Lozano JD, Ruiz-Martinez C, Brea-Hernando A Abstract BACKGROUND: Bendopnea is a symptom described in heart failure (HF) that is related to short-term prognosis; however, its frequency and characteristics in respiratory diseases such as OSAS is still unknown. This study was carried...
Wed Aug 26, 2020 14:40
Related Articles Efficacy of Adenoidectomy for the Treatment of Mild Sleep Apnea in Children. Otolaryngol Head Neck Surg. 2020 Aug 25;:194599820950719 Authors: Tipold A, Vazifedan T, Baldassari CM Abstract OBJECTIVES: (1) To assess outcomes in children undergoing adenoidectomy for the treatment of mild obstructive sleep apnea (OSA). (2) To identify clinical factors that predict which children will have persistent obstruction following adenoidectomy....
Wed Aug 26, 2020 14:40
[Advances in research on Crouzon syndrome and related ophthalmic complications]. Zhonghua Yan Ke Za Zhi. 2020 Jul 11;56(7):544-548 Authors: Xie F, Zhao KX, Zhang W Abstract Crouzon syndrome is an autosomal dominant disorder characterized by acrocephaly, exophthalmos, hypertelorism, strabismus, parrot-beaked nose, and hypoplastic maxilla. It is usually caused by a pathogenic mutation in the fibroblast growth factor receptor 2 gene and premature...
Wed Aug 26, 2020 16:15
[Clinical characteristics and surgical treatment analysis of paranasal ossifying fibroma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr;34(4):351-355 Authors: Zhang X, Pang W, Jiang Y, Chen X, Zhang M, Li N, Yan X, Chen M, Ju J Abstract Objective:To analyze the clinical features and discuss the treatment of ossifying fibroma in the nasal cavity and sinuses. Method:The patients were performed surgical treatment after admission. 6...
Wed Aug 26, 2020 16:15
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