Objective. Elastase-induced aneurysms in rabbits have been proposed as a preclinical tool for device development, but there is still much deficiency in those aneurismal models. So we need to explore the efficient and convenient animal models for the investigation of intracranial aneurysms. Then, we compared and analyzed three methods of elastase-induced carotid artery aneurysms in rabbits and aimed to find a simple, effective, and reproducible method for creating elastase-induced aneurysms. Methods....
Wed Aug 26, 2020 17:35
Background. Globally, electronic information and communication technology has been applied and much expanded in the healthcare industry. However, in developing counties including Ethiopia, EMR system adoption and utilization for medical practice are still inconsistent, and healthcare institutions which started utilization currently have also failed to sustain. A desirable readiness of healthcare experts is mandatory to expand digital health service delivery. Thus, this study is aimed at estimating...
Wed Aug 26, 2020 17:20
The Semantic Web and Linked Data concepts and technologies have empowered the scientific community with solutions to take full advantage of the increasingly available distributed and heterogeneous data in distinct silos. Additionally, FAIR Data principles established guidelines for data to be Findable, Accessible, Interoperable, and Reusable, and they are gaining traction in data stewardship. However, to explore their full potential, we must be able to transform legacy solutions smoothly into the...
Wed Aug 26, 2020 17:20
In this paper, we have used an agent-based stochastic tumor growth model and presented a mathematical and theoretical perspective to cancer therapy. This perspective can be used to theoretical study of precision medicine and combination therapy in individuals. We have conducted a series of in silico combination therapy experiments. Based on cancer drugs and new findings of cancer biology, we hypothesize relationships between model parameters which in some cases represent individual genome characteristics...
Wed Aug 26, 2020 17:05
Objective. To explore the possible role of miR-499a-3p in the function of primary human umbilical vein endothelial cells (HUVECs) and the expression of ADAM10 in primary HUVEC. Method. miR-499a-3p was first transfected into primary HUVECs via lentivirus vector. The viability, proliferation, and migration of stable transfected primary HUVEC were then determined by flow cytometry, CCK8 assays, scratch tests, and Transwell tests. The transcription of miR-499a-3p and ADAM10 was examined by reverse transcription-polymerase...
Wed Aug 26, 2020 10:35
In clinical cancer research, it is a hot topic on how to accurately stratify patients based on genomic data. With the development of next-generation sequencing technology, more and more types of genomic features, such as mRNA expression level, can be used to distinguish cancer patients. Previous studies commonly stratified patients by using a single type of genomic features, which can only reflect one aspect of the cancer. In fact, multiscale genomic features will provide more information and may...
Wed Aug 26, 2020 10:35
Background. In recent years, health insurance (HI) has been chosen by many low- and middle-income countries to obtain an important health policy target—universal health coverage. Vietnam has recently introduced the Revised Health Insurance Law, and the effects of the voluntary health insurance (VHI) and heavily subsidised health insurance (HSHI) programmes have not yet been analysed. Therefore, this study is aimed at examining the impact of these HI programmes on the utilisation of health care services...
Wed Aug 26, 2020 10:05
Robotic surgical assistants, such as the da Vinci systems from Intuitive Surgical, are now routinely used during laparoscopic procedures to improve operative precision, flexibility, and to manipulate multiple tools at once. Such devices can be quite complex inside and so they tend to be quite large, often taking up much of the space of an operating room. Moreover, they are still too cumbersome to operate on particularly fragile tissues and smaller anatomical structures. Now, a pair...
Wed Aug 26, 2020 19:00
Publication date: Available online 26 August 2020Source: Medical Image AnalysisAuthor(s): Huazhu Fu, Fei Li, Xu Sun, Xingxing Cao, Jingan Liao, José Ignacio Orlando, Xing Tao, Yuexiang Li, Shihao Zhang, Mingkui Tan, Chenglang Yuan, Cheng Bian, Ruitao Xie, Jiongcheng Li, Xiaomeng Li, Jing Wang, Le Geng, Panming Li, Huaying Hao, Jiang Liu
Wed Aug 26, 2020 15:03
Background Changes in land use trigger environmental changes that can lead to decreased biodiversity and species loss. The liver is an essential detoxification organ that reflects systemic physiological responses to environmental changes. Here, we tested whether contrasting land use patterns influence the amount of substances from the hepatic cellular catabolism and melanomacrophages (MMs) of five anuran species in the Brazilian Cerrado. Methods We collected the same five species of pond-dwelling...
Wed Aug 26, 2020 03:00
Corynebacterium pseudotuberculosis is a pathogen of veterinary relevance diseases, being divided into two biovars: equi and ovis; causing ulcerative lymphangitis and caseous lymphadenitis, respectively. The isolation and sequencing of C. pseudotuberculosis biovar ovis strains in the Northern and Northeastern regions of Brazil exhibited the emergence of this pathogen, which causes economic losses to small ruminant producers, and condemnation of carcasses and skins of animals. Through the pan-genomic...
Wed Aug 26, 2020 03:00
The study analysed the effect of shelterwood-cut strips on the outermost crown profiles and crown characteristics of naturally regenerated Pinus tabuliformis saplings in northeastern China. A total of 49 regenerated saplings from shelterwood-cut strips and 30 from uncut strips were collected. Nonlinear quantile regression was used to develop the outermost crown profile model for the saplings from the shelterwood-cut and uncut strips. The quantile value suitable for describing the outermost crown...
Wed Aug 26, 2020 03:00
Extracellular vesicles (EVs) are cell-derived structures that transport proteins, lipids and nucleic acids between cells, thereby affecting the phenotype of the recipient cell. As the content of EVs reflects the status of the originating cell, EVs can have potential as biomarkers. Identifying EVs, including their cells of origin and their cargo, may provide insights in the pathophysiology of psychosis. Here, we present an in-depth analysis and proteomics of EVs from peripheral blood in patients (n = 25)...
Wed Aug 26, 2020 03:00
Background The architecturally important coral species Acropora cervicornis and A. palmata were historically common in the Caribbean, but have declined precipitously since the early 1980s. Substantial resources are currently being dedicated to coral gardening and the subsequent outplanting of asexually reproduced colonies of Acropora, activities that provide abundant biomass for both restoration efforts and for experimental studies to better understand the ecology of these critically...
Wed Aug 26, 2020 03:00
Background Salvia eigii., Salvia hierosolymitana and Salvia viridis are native to the Mediterranean region, and are used in traditional medicine for the treatment of many ailments. In the current investigation, the methanolic extracts obtained from the air dried aerial parts of S. eigii, S. hierosolymitana and S. viridis from Jordan were screened for their total phenolics content (TPC), total flavonoids content (TFC) and their in vitro antioxidant activity. Additionally, the presence...
Wed Aug 26, 2020 03:00
Publication date: Available online 26 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Danielle S. Bitterman, Kathryn A. Winter, Theodore S. Hong, Charles S. Fuchs, William F. Regine, Ross A. Abrams, Howard Safran, John P. Hoffman, Al B. Benson, Timothy Kasunic, Mary Mulcahy, James F. Strauss, Thomas DiPetrillo, Philip J. Stella, Yuhchyau Chen, John P. Plastaras, Christopher H. Crane
Wed Aug 26, 2020 15:40
Publication date: Available online 25 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Christopher J. Anker, Jadranka Dragovic, Joseph M. Herman, Nancy A. Bianchi, Karyn A. Goodman, William E. Jones, Timothy J. Kennedy, Rachit Kumar, Percy Lee, Suzanne Russo, Navesh Sharma, William Small, W. Warren Suh, Leila Tchelebi, Salma K. Jabbour
Wed Aug 26, 2020 15:40
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